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While smoking was once seen as a mark of sophistication, smokers are now often stereotyped as unhealthy and dirty, even among smokers themselves

The damage to the dermal connective tissue, including the reduced levels of the different types of collagens due to a decrease in their synthesis and an increase in their degradation via the MMPs, is the hallmark of extrinsic skin aging 32,33,34,35,36,37

For example, leachates with a concentration of only 1.8 smoked filters/L are sufficient to cause mortality (LC50) in marine fish Atherinops affinis in a 96-h exposure [39]